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Case Report | OPEN ACCESS

Clinical efficacy and anti-recurrence effect of isatis root eye drops combined with ganciclovir eye drops in the treatment of Herpes simplex keratitis; a case report

Liang Yin1 , Mingxue Zhang1, Hongguang Jin2

1Ophthalmology Department, The General Hospital of Tianjin Medicine University, Tianjin 300052, China; 2Department of Traditional Chinese Medicine and Acupuncture, The General Hospital of Tianjin Medicine University, Tianjin 300052, China.

For correspondence:-  Liang Yin   Email: yl332332@163.com

Accepted: 11 January 2022        Published: 28 February 2021

Citation: Yin L, Zhang M, Jin H. Clinical efficacy and anti-recurrence effect of isatis root eye drops combined with ganciclovir eye drops in the treatment of Herpes simplex keratitis; a case report. Trop J Pharm Res 2022; 21(2):433-438 doi: 10.4314/tjpr.v21i2.29

© 2022 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Purpose: The rate of gastrointestinal adenomatous polyps, often regarded as precancerous lesions, developing into cancer is 40 – 70 %. Endoscopic resection has been the preferred method for treating gastric polyps since the late 1960s. Surgical removal of polyps continues to play an important role in the treatment of polyps; however, the efficacy of such treatment cannot be guaranteed, and polyps may recur.
Case presentation: Here, we report a 44-year-old man suffering from gastrointestinal polyps who refused surgical treatment and instead was treated with traditional Chinese herbal medicine (TCHM) for approximately 1 year. The patient was diagnosed with “qi deficiency and dampness syndrome” based on traditional Chinese medicine theory and was treated with the TCHM “strengthen qi and remove dampness formula”, referred to as the shen-ling-bai-zhu powder/decoction.
Conclusion: This case suggests that TCHM may play an important role in the treatment of gastrointestinal polyps. Relevant data are, however, limited and a randomized controlled trial is needed to confirm TCHM efficacy in a larger population.

Keywords: Case study, Gastrointestinal polyps, Traditional Chinese herbal medicine, Shen-ling-bai-zhu powder

Impact Factor
Thompson Reuters (ISI): 0.523 (2021)
H-5 index (Google Scholar): 39 (2021)

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